Polo-like kinase 1 (Plk1) in non-melanoma skin cancers
نویسندگان
چکیده
منابع مشابه
Incidence of non-melanoma skin cancers in Isfahan
Background and aim: Non-melanoma skin cancers (NMSC) are one of the most prevalent malignancies of the human. Although the morality rate is not high for these cancers, they may cause high morbility for the patients. In addition to the skin type, factors such as sun exposure, head and neck radiotherapy, inappropriate use of sunscreen and cultural changes may increase the incidence of these...
متن کاملSurvival and Recurrence in Non-melanoma Skin Cancers of scalp
Abstract Introduction: Non-melanoma scalp skin cancers (NMSCs) including squamous cell carcinomas (SCCs) and basal cell carcinomas (BCCs) are common. To manage such cancers, especially SCCs, more attention should be paid to their invasive characteristics. Mortality surveillance of SCCs and BCCs of scalp helps to choose proper approaches. Methods: The current retrospective, descriptive study w...
متن کاملSurvival and Recurrence in Non-melanoma Skin Cancers of scalp
Abstract Introduction: Non-melanoma scalp skin cancers (NMSCs) including squamous cell carcinomas (SCCs) and basal cell carcinomas (BCCs) are common. To manage such cancers, especially SCCs, more attention should be paid to their invasive characteristics. Mortality surveillance of SCCs and BCCs of scalp helps to choose proper approaches. Methods: The current retrospective, descriptive study w...
متن کاملPLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy
Mechanistic target of rapamycin complex 1 (MTORC1) and polo like kinase 1 (PLK1) are major drivers of cancer cell growth and proliferation, and inhibitors of both protein kinases are currently being investigated in clinical studies. To date, MTORC1's and PLK1's functions are mostly studied separately, and reports on their mutual crosstalk are scarce. Here, we identify PLK1 as a physical MTORC1 ...
متن کاملKiller Cell Immunoglobulin-Like Receptors (KIRs) Genotype and Haplotype Analysis in Iranians with Non-Melanoma Skin Cancers
Background: The innate immune system against malignancies is mainly orchestrated by natural killer cells, which carry out killing mechanisms by using their receptors, such as killer immunoglobulin-like receptors (KIRs). This study was designed to determine the diversity of KIR genes in non-melanoma skin cancers. Methods: A total of 160 subjects with skin cancer, including 60 cases of squamous c...
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ژورنال
عنوان ژورنال: Cell Cycle
سال: 2009
ISSN: 1538-4101,1551-4005
DOI: 10.4161/cc.8.17.9413